Drug-Induced Valvular Heart Disease

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Informação do Produto

ISBN9781616689780
EditoraNova Science Publishers Inc
Data de Publicação23/05/2011
Preço (iva excl.)€ 66,89
Imposto€ 4,01
Preço (iva inc.)€ 70,90
Disponibilidade1 unidade em armazém externo

Descrição do Produto

The notion that drugs can induce valvular heart disease (VHD) has occurred since the sixties and has received a lot of attention in recent years. Overstimulation of the serotonin 2B receptor (5-HT2B) leads to valvular fibroblast proliferation and thickening of the valvular leaflets with reduced mobility and regurgitation as a consequence. This book focuses on different aspects of this distinct kind of valvulopathy including pathophysiology of drug-induced VHD, histopathological and echocardiographic characteristics,drugs associated with VHD, the influence of cumulative drug dose and risk factors and others.